Download Adult Acute Lymphocytic Leukemia: Biology and Treatment by Charles A. Schiffer (auth.), Anjali S. Advani, Hillard M. PDF

By Charles A. Schiffer (auth.), Anjali S. Advani, Hillard M. Lazarus (eds.)

The present explosion of recent parts of controversy within the therapy of acute lymphocytic leukemia in adults and teenagers makes this complete booklet a miles wanted reference for hematologists and oncologists. This e-book assembles best specialists from all over the world to hide the complete spectrum of ALL subtypes and their remedies. particular issues of debate comprise symptoms for allogeneic bone marrow transplant in first entire remission, the function of minimum residual ailment in making remedy judgements, the remedy of teenagers, and the therapy of Philadelphia chromosome optimistic ALL with the appearance of the tyrosine kinase inhibitors. this can be the 1st booklet to concentration completely at the grownup ALL sufferer. It presents an entire review of analysis, molecular pathogenesis, evaluate, and remedy for this crucial sufferer population.

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Clinical significance of cytogenetic abnormalities in adult acute lymphoblastic leukemia. Blood, 91(11), 3995–4019. 48. , et al. (2008). Impact of cytogenetics on the outcome of adult acute lymphoblastic leukemia: Results of Southwest Oncology Group 9400 study. Blood, 111(5), 2563–2572. 49. Moorman, A. , et al. (2007). Karyotype is an independent prognostic factor in adult acute lymphoblastic leukemia (ALL): Analysis of cytogenetic data from patients treated on the Medical Research Council (MRC) UKALLXII/Eastern Cooperative Oncology Group (ECOG) 2993 trial.

Mortuza, F. , et al. (2002). Minimal residual disease tests provide an independent predictor of clinical outcome in adult acute lymphoblastic leukemia. Journal of Clinical Oncology, 20(4), 1094–1104. 83. , et al. (2006). Clinical significance of minimal residual disease quantification in adult patients with standard-risk acute lymphoblastic leukemia. Blood, 107(3), 1116–1123. 84. , et al. (2007). Molecular relapse in adult standard-risk ALL patients detected by prospective MRD monitoring during and after maintenance treatment: Data from the GMALL 06/99 and 07/03 trials.

Current Oncology Reports, 5(5), 413–418. 88. , et al. (1997). A prospective study of minimal residual disease in childhood B-lineage acute lymphoblastic leukaemia: MRD level at the end of induction is a strong predictive factor of relapse. British Journal Haematology, 98(1), 140–146. 89. van Dongen, J. , et al. (1998). Prognostic value of minimal residual disease in acute lymphoblastic leukaemia in childhood. Lancet, 352(9142), 1731–1738. 90. , et al. (1998). Immunological detection of minimal residual disease in children with acute lymphoblastic leukaemia.

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